CFDA#
93.853
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Funder Type
Federal Government
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IT Classification
B - Readily funds technology as part of an award
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Authority
National Institutes of Health (NIH)
Summary
Exploratory/Developmental Grants (R21) are supported by NIA in its four extramural programs (Division of Aging Biology, Division of Behavioral and Social Research, Division of Neuroscience, and Division of Geriatrics and Clinical Gerontology). Topics currently being solicited through this mechanism are available from the individual program Web sites. Interested applicants should follow instructions in the NIH R21 PA.
History of Funding
None is available.
Additional Information
Division of Aging Biology accepts R21 applications in areas providing new avenues of research on the molecular, cellular, physiological, and genetic mechanisms of aging within the mission of the program.
Applications in the following areas are particularly encouraged:
- The molecular basis of Hutchinson-Gilford syndrome;
- The development of novel animal models of aging, particularly for identifying genes and biochemical pathways regulating longevity;
- The role of stem cells in preventing adverse age-related changes due to loss of specific cell types.
Division of Behavioral and Social Research accepts R21 applications in its areas of emphasis, including:
- Health Disparities
- Aging Minds
- Increasing Health Expectancy
- Health, Work, and Retirement
- Interventions and Behavior Change
- Genetics, Behavior, and the Social Environment
- The Burden of Illness and the Efficiency of Health System
Division of Neuroscience accepts R21 applications in all areas of NNA's mission focusing on research to understand the aging process in the structure and functioning of the nervous system and the brain-behavior relationship. An important component of this program is the support of basic, clinical, and epidemiological studies of Alzheimer's disease and related dementias of aging. Of special interest are innovative and high-impact studies focused on identifying, preventing, and treating neurodegenerative disorders and cognitive declines associated with aging.
Division of Geriatrics and Clinical Gerontology accepts R21 applications involving research on health and disease in the aged and research on aging during the human lifespan and its relationships to health outcomes, consistent with the mission of the program. Specifically, i) Longevity associated variants (LAV) such as ApoE2 to improve understanding of physiologic and cellular differences attributable to the protective variant(s) and how they mediate differential effects on longevity and risk for age-related conditions. ii) Identification of potential therapeutic targets based on LAV(s)for interventions that prevent or ameliorate aging-related diseases and enhance human life and health span consistent with the mission of our program.
The Geriatrics and Clinical Gerontology Program accepts R21 applications involving research on health and disease in the aged and research on aging during the human lifespan and its relationships to health outcomes, consistent with the program's mission.
Eligibility Details
Higher Education Institutions
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)
Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession
Other
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Institutions)
Foreign Institutions
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
- Foreign components are allowed.
Deadline Details
Applications are due February 16, June 16, and October 16 annually.
Award Details
Direct costs are limited to $275,000 over a two-year period, with no more than $200,000 in direct costs allowed in any single year. No cost-sharing is required. The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
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